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Related Experiment Videos

Lactose intolerance in Iran.

M Sadre, K Karbasi

    The American Journal of Clinical Nutrition
    |September 1, 1979
    PubMed
    Summary

    Lactose malabsorption is common in Iranians, affecting 68% of individuals and increasing with age. While many malabsorb lactose, only some experience lactose intolerance symptoms.

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    Area of Science:

    • Gastroenterology
    • Human Physiology
    • Nutritional Science

    Background:

    • Lactose malabsorption is a widespread condition.
    • Understanding its prevalence and clinical manifestations is crucial for public health.
    • Age-related differences in lactose digestion are well-documented in various populations.

    Purpose of the Study:

    • To determine the prevalence of lactose malabsorption and intolerance in an Iranian population.
    • To investigate the relationship between age and lactose malabsorption.
    • To assess the correlation between lactose malabsorption and the occurrence of clinical symptoms.

    Main Methods:

    • A cohort of 105 Iranian subjects aged 4 months to 25 years participated.
    • Subjects underwent a lactose tolerance test involving blood glucose level monitoring after lactose ingestion.
    • Clinical symptoms of lactose intolerance were recorded and analyzed.

    Main Results:

    • 68% of the subjects exhibited lactose malabsorption based on low blood glucose response.
    • Lactose malabsorption prevalence increased significantly with age, from 31% in children under 3 years to 86% in adults.
    • Only 57% of lactose malabsorbers reported clinical symptoms, with symptom prevalence highest in adults and lowest in young children.

    Conclusions:

    • Lactose malabsorption is highly prevalent in the Iranian population, with a marked increase in adults.
    • A significant portion of individuals with lactose malabsorption do not exhibit clinical symptoms of lactose intolerance.
    • Age is a critical factor influencing both lactose malabsorption and the manifestation of intolerance symptoms.

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