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Clinical experience with the Lillehei-Kaster valve prosthesis.

H H Zwart, G Hicks, B Schuster

The Annals of Thoracic Surgery

|August 1, 1979

Summary

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The Lillehei-Kaster valve demonstrated moderate hospital mortality but offered significant long-term survival and clinical improvement for aortic and mitral valve replacement patients.

Area of Science:

Cardiovascular Surgery
Biomaterials Science
Clinical Outcomes Research

Background:

The Lillehei-Kaster valve is a mechanical prosthetic heart valve.
Evaluating long-term outcomes of prosthetic valves is crucial for patient management.

Purpose of the Study:

To assess the clinical outcomes, including mortality and thromboembolism, of the Lillehei-Kaster valve in patients undergoing aortic and mitral valve replacement.

Main Methods:

Retrospective analysis of 215 patients who received the Lillehei-Kaster valve over a 7-year period.
Separate evaluation of outcomes for aortic valve replacement (81 patients) and mitral valve replacement (108 patients).
Data collection included hospital mortality, long-term mortality, thromboembolic events, and actuarial survival.

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Main Results:

Aortic valve replacement: 21% hospital mortality, 5% long-term mortality, 2.6/100 patient-years thromboembolism, 96% 5-year survival.
Mitral valve replacement: 20% hospital mortality, 13% long-term mortality, 5.0/100 patient-years thromboembolism, 81% 5-year survival.
Majority of patients experienced clinical improvement; 15 had double-valve replacement, 11 had concurrent coronary revascularization.

Conclusions:

The Lillehei-Kaster valve provided acceptable long-term survival and clinical benefit for both aortic and mitral valve replacement, despite significant early mortality.
Thromboembolism rates were observed in both patient groups.
Further research may focus on optimizing anticoagulation strategies to mitigate thromboembolic risks.