Related Experiment Video
Updated: Jul 8, 2026

Transthoracic Echocardiography in Mice
Published on: May 29, 2010
Evaluation of the left ventricular ejection function by means of single beam echocardiography
Abstract:
Echocardiographic examination of the left ventricle was performed in a group of 50 patients with various heart diseases. Five methods proposed for left ventricular pump function calculation were used, based on measurements of ventricular end-diastolic diameters. The results have shown that all tested methods of determining the ejection fraction or its functional equivalent (fractional shortening) correlate significantly with the ejection fraction obtained from the considered angiocardiographic technique. The closest correlation (r=0.771) was found when the ejection fraction was calculated from volume values determined by the cubed formula. Among other methods, that of fractional shortening and ejection fraction derived from those values seemed to be well interpretable. Other methods of ejection fraction calculation have a rationale in some cases, but have also their specific limitations.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...

