Coarctation of the aorta operated upon in infancy. Long-term follow-up
Insights
Infant surgery for coarctation of the aorta may not prevent later hypertension or recoarctation. Long-term follow-up is crucial for these patients, and elective infant surgery requires further evidence.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Long-term Health Outcomes
Background:
- Coarctation of the aorta is a congenital heart defect requiring surgical intervention.
- Early surgical repair in infancy is a common practice.
- Long-term outcomes and potential complications require further investigation.
Purpose of the Study:
- To evaluate the long-term outcomes of surgical repair for coarctation of the aorta in infancy.
- To assess the incidence of recoarctation and hypertension following early surgical intervention.
- To determine the relationship between age at operation and long-term complications.
Main Methods:
- A long-term follow-up study involving 14 patients operated for coarctation of the aorta in infancy.
- Median age at operation was 4 months.
- Follow-up duration ranged from 7 to 22 years, with a mean age of 16 years at follow-up.
Main Results:
- Recoarctation was present in 6 out of 14 patients, with no correlation to the age at initial operation.
- Three patients had overlooked concomitant aortic valve anomalies.
- Systolic and diastolic blood pressure were significantly elevated at follow-up, with 2 patients exhibiting diastolic hypertension.
Conclusions:
- Infant surgery for coarctation of the aorta does not consistently prevent later hypertension or recoarctation.
- The risks associated with elective infant surgery, including recoarctation, warrant cautious consideration pending more long-term data.
- Maintaining long-term follow-up for these patients is essential.
Abstract:
A long-term follow-up study was performed in 14 patients, operated for coarctation of the aorta in infancy. The median age at operation was 4 mth. Mean and median age at follow-up were 16 yr, and the follow-up time varied between 7 and 22 yr (mean and median 15 yr). At follow-up recoarctation was or had been present in 6 patients; there was no relation between the development of recoarctation and the age at operation. Concomitant aortic valve anomaly had been overlooked at the initial investigation in 3 patients. The systolic and diastolic blood pressure at follow-up was significantly elevated above the mean of normals; 2 of 8 patients without recoarctation clearly had diastolic hypertension. It seems as if even operation in infancy does not prevent hypertension later in childhood or adolescence in some of the patients, and it hardly seems justified to perform elective operations for coarctation of the aorta in infancy with the appreciable risk of recoarctation, until more long-term follow-up results are known. The patients should not be lost to follow-up.
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