Related Experiment Video
Updated: Aug 13, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Abstract:
1. Two oxaloacetate decarboxylases of rat liver are described; one is mitochondrial with no metal ion requirement and activity in the alkaline pH region; the other is cytoplasmic with Mn(2+) or Mg(2+) requirement and activity around pH5. 2. A method for the partial purification of the mitochondrial enzyme is described. 3. The apparent K(m) of the mitochondrial enzyme is 0.23mm. 4. Inhibition of the mitochondrial enzyme by substrate, CoA, acetyl-CoA, citrate and phosphoenolpyruvate is described.
More Related Videos
Related Concept Videos
Oxidations of Aldehydes and Ketones to Carboxylic Acids
Aldehydes readily undergo oxidation in strong oxidizing agents such as potassium permanganate and chromic acid. The oxidation can also be carried out using mild oxidizing agents such as silver oxide. In fact, aldehydes can be easily oxidized...
Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation
The carbonyl center is activated by...
Loss of Carboxy Group as CO2: Decarboxylation of β-Ketoacids
Acid-Catalyzed Aldol Addition Reaction
Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives
Phase II Reactions: Acetylation Reactions
The substrates for acetylation are typically drugs or their metabolites with an amino, sulfonamide, or hydrazine functional group. Acetylation can occur at several points in the drug molecule, including primary, secondary, and...

