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Hyperosmolar coma as etiological factor in the CNS radiation syndrome of rats

J Kabal, L P Kirschner, L J Parkhurst

Experientia

|July 15, 1979

Abstract:

Supralethal dose of whole-body or trunk but not head-irradiation in rats induced hyperosmolar coma accompanied by hypernatremia and hyperkalemia. This clinical entity has presented the symptoms of the CNS radiation syndrome with a characteristic short survival time.

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