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Isolation of type-C viruses from the Asian feral mouse Mus musculus molossinus
International Journal of Cancer
|February 15, 1975
Abstract:
N-tropic and xenotropic type-C viruses have been isolated from the wild Asian mouse subspecies M. musculus molossinus. By host range, morphologic and some immunologic criteria these viruses appear closely related to the previously studied murine type-C viruses isolated from highly inbred laboratory strains of mice.
Insights
N-tropic and xenotropic type-C viruses were found in wild Asian mice (M. musculus molossinus). These newly isolated viruses share characteristics with known murine type-C viruses from laboratory mice.
Area of Science:
- Virology
- Mouse Genetics
Background:
- Murine type-C viruses are commonly found in laboratory mice.
- Understanding viral diversity in wild populations is crucial.
Purpose of the Study:
- To isolate and characterize type-C viruses from wild Asian mice (M. musculus molossinus).
- To compare these novel isolates with known murine type-C viruses.
Main Methods:
- Isolation of N-tropic and xenotropic type-C viruses.
- Analysis of host range, morphology, and immunological properties.
Main Results:
- Successfully isolated N-tropic and xenotropic type-C viruses from M. musculus molossinus.
- The isolated viruses showed close similarities to previously studied murine type-C viruses.
Conclusions:
- Wild Asian mice harbor type-C viruses.
- These viruses are evolutionarily related to those found in laboratory mouse strains.