Related Experiment Video
Updated: Aug 18, 2026

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
Side effects in methadone patients: a survey of self-reported complaints
Abstract:
Fifty-one patients in a methadone maintenance program completed a questionnaire containing 38 complaints upon admission and after 3 and 9 months in treatment. The questionnaire contained a graded scale of five possible responses from "no problem" to "a very bad problem." Only three complaints at 3 months and five complaints at 9 months showed an increase in the percentage of clients reporting them as a problem compared to before methadone matinenance (BMM). When analyzed by summed mean, only one complaint at 3 months and two at 9 months showed an increase in severity on the graded scale compared to BMM. However, when each patient's responses were analyzed as to whether problems showed no change in severity, were improved, or increased in severity comparing BMM and after 9 months of methadone, 11 of 38 complaints showed a significant number of patients reporting them as more severe.
More Related Videos
10:17High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
09:29Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Related Concept Videos
Drug Dependence
Opioid Analgesics: Morphine and Other Natural Cogeners
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Therapeutic Drug Monitoring: Affecting Factors
Toxidromes: Clinical Features