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Updated: Aug 11, 2026

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses
Published on: March 14, 2012
Blue-sensitive cones of the cat produce a rodlike electroretinogram
Abstract:
Two cone mechanisms are identifiable in the strongly yellow light-adapted electroretinogram (ERG) of the arterially perfused cat eye. One has its maximum spectral sensitivity near 555 nm; the other has its maximum near 450 nm. The former cone system produces a much larger signal with characteristics of a typical cone or inhibitory ERG. The latter cone system produces a small, saturable signal (less than 5 microV) which resembles a rodlike or excitatory ERC. The results imply that the latter ERG is generated by blue-sensitive cones, which form a small fraction of the total cone population and share some physiological and perhaps anatomical properties of rods.
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