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Updated: Aug 11, 2026

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
Published on: May 25, 2011
The calcium-dependent slow after-hyperpolarization in myenteric plexus neurones with tetrodotoxin-resistant action
Abstract:
Intracellular recordings were made from neurones of the myenteric plexus of the guinea-pig ileum. The slow after-hyperpolarization which followed an action potential in some neurones was abolished by Mn(++), La(+++) and by solutions which contained no Ca(++). In these neurones, the action potential and the slow after-hyperpolarization persisted in Na(+)-free solutions or in the presence of tetrodotoxin (2 muM). The findings suggest that an inward Ca(++) current during the action potential is essential for the slow after-hyperpolarization.
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