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Increased physical growth after successful antireflux operation

R W Merrell, J J Mowad

    The Journal of Urology
    |October 1, 1979
    PubMed

    Insights

    Successful surgical repair of pediatric vesicoureteral reflux (VUR) significantly improves physical growth. Postoperative growth percentile increased by an average of 81% in children after ureteroneocystostomy.

    Area of Science:

    • Pediatric nephrology
    • Pediatric urology
    • Growth and development

    Background:

    • Vesicoureteral reflux (VUR) with infection can impede renal growth in children.
    • Previous studies suggest renal growth can resume or accelerate after VUR repair.
    • The impact of VUR repair on overall physical growth remains under-documented.

    Purpose of the Study:

    • To evaluate the effect of surgical repair of VUR on the physical growth of pediatric patients.
    • To analyze preoperative and postoperative physical growth curves in children undergoing ureteroneocystostomy.

    Main Methods:

    • Retrospective analysis of 35 consecutive pediatric patients.
    • Patients underwent ureteroneocystostomy for treatment of VUR.
    • Comparison of preoperative and postoperative physical growth percentiles.

    Main Results:

    • A significant increase in the postoperative physical growth percentile was observed.
    • The average increase in growth percentile was 81% after surgery.
    • This indicates a substantial positive impact on physical development post-VUR repair.

    Conclusions:

    • Surgical repair of VUR, specifically ureteroneocystostomy, promotes significant physical growth in pediatric patients.
    • The findings highlight the importance of addressing VUR to optimize children's overall physical development.
    • Further research can explore long-term growth outcomes and mechanisms driving accelerated growth.

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