[Differences in the character and intensity of morphologic changes in the peritoneal cavity and lungs resulting from...

Results are submitted of studies on the influence exerted by cement dust, introduced into the peritoneal cavity and lung of experimental animals. The difference recorded are explained by the low free silicon dioxide content in the cement investigated and to the presence of additional chemical ingredients. The inference is reached that in the course of testing dusts with high free silicon dioxide content and determinations of the fibrinogenous action of the dust investigated, the two methods yield approximately identical results. Anyway, during studies of dusts with low silica content in the presence of additional chemical components, and determinations of their general toxic and biological action, the results obtained by either of the methods should be distinguished and separately evaluated. The organs of the pleural cavity, respectivly the lung, are more feasible for investigation of the fibrinogenic activity of dusts, whilst the peritoneal cavity is more suitable for investigation of the cumulative action of dusts with fibrous and toxic effect.