Binding of basic and acidic drugs to rat tissue subcellular fractions

Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ.

Molecular psychiatry·2014

Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.

Molecular psychiatry·2014

Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.

Translational psychiatry·2013

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.

Molecular psychiatry·2012

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.

Molecular psychiatry·2012

[Not Available].

NTM·2001

Triclosan induces DNA damage in human ovarian granulosa cells via mitochondrial superoxide overproduction mediated by suppressed glutathione synthesis.

Chemico-biological interactions·2026

PGAM5-mediated VDAC1 oligomerization Facilitates Ponatinib-Induced Cardiotoxicity via Disrupting the Mitophagy-Mitochondrial unfolded protein response Synergistic Defense Crosstalk.

Chemico-biological interactions·2026

Novel environmental contaminant 6PPD-quinone promotes malignant phenotypes in colorectal cancer cells and identifies candidate response-associated genes.

Chemico-biological interactions·2026

ERS-mediated metabolic toxicity: The IRE1α/XBP1s pathway as a critical driver of Cr(VI)-Induced disruption in glucose and lipid metabolism.

Chemico-biological interactions·2026

Endoplasmic reticulum stress is involved in chronic chlorpyrifos-induced jejunal barrier injury in weaned mice.

Chemico-biological interactions·2026

ADRB2 Modulates Asbestos-Induced Pleural Mesothelioma Progression by Influencing IL-17/NF-κB-Related Inflammatory Signalling: An Integrated Network Toxicology, Multi-Omics and Experimental Study.

Chemico-biological interactions·2026

Membrane Phase Separation: An Emerging Biophysical Perspective on Food-Derived Bioactive Peptides.

Journal of agricultural and food chemistry·2026

Neuropharmacological and behavioral characterization of 3F-phenetrazine, a novel amphetamine-like substance, in male mice and rats.

European journal of pharmacology·2026

A practical approach to estimate the potency of an antagonist in a functional experiment with isolated preparations of rat aorta.

Advances in physiology education·2026

Species Divergence in Oxytocin-Dependent Yawning on a Conserved Glutamatergic Erection Circuit.

Neuroscience bulletin·2026

The Combination of Buprenorphine and Pregabalin in the Management of Peripheral Neuropathic Pain: A Phase IV, Randomized, Double-Blind and Placebo-Controlled Clinical Trial.

European journal of pain (London, England)·2026

Safety, Pharmacokinetics, Food effect, and Pharmacodynamics of AJM347, a Selective α4β7 Integrin Antagonist: A First-in-Human Single- and Multiple-Ascending Dose Study in Healthy Male Volunteers.

Journal of clinical pharmacology·2026

Related Experiment Videos

Binding of basic and acidic drugs to rat tissue subcellular fractions

Related Concept Videos

Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ.

Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.

Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.

[Not Available].

Triclosan induces DNA damage in human ovarian granulosa cells via mitochondrial superoxide overproduction mediated by suppressed glutathione synthesis.

PGAM5-mediated VDAC1 oligomerization Facilitates Ponatinib-Induced Cardiotoxicity via Disrupting the Mitophagy-Mitochondrial unfolded protein response Synergistic Defense Crosstalk.

Novel environmental contaminant 6PPD-quinone promotes malignant phenotypes in colorectal cancer cells and identifies candidate response-associated genes.

ERS-mediated metabolic toxicity: The IRE1α/XBP1s pathway as a critical driver of Cr(VI)-Induced disruption in glucose and lipid metabolism.

Endoplasmic reticulum stress is involved in chronic chlorpyrifos-induced jejunal barrier injury in weaned mice.

ADRB2 Modulates Asbestos-Induced Pleural Mesothelioma Progression by Influencing IL-17/NF-κB-Related Inflammatory Signalling: An Integrated Network Toxicology, Multi-Omics and Experimental Study.

Membrane Phase Separation: An Emerging Biophysical Perspective on Food-Derived Bioactive Peptides.

Neuropharmacological and behavioral characterization of 3F-phenetrazine, a novel amphetamine-like substance, in male mice and rats.

A practical approach to estimate the potency of an antagonist in a functional experiment with isolated preparations of rat aorta.

Species Divergence in Oxytocin-Dependent Yawning on a Conserved Glutamatergic Erection Circuit.

The Combination of Buprenorphine and Pregabalin in the Management of Peripheral Neuropathic Pain: A Phase IV, Randomized, Double-Blind and Placebo-Controlled Clinical Trial.

Safety, Pharmacokinetics, Food effect, and Pharmacodynamics of AJM347, a Selective α4β7 Integrin Antagonist: A First-in-Human Single- and Multiple-Ascending Dose Study in Healthy Male Volunteers.

Related Experiment Videos

Binding of basic and acidic drugs to rat tissue subcellular fractions

Related Concept Videos

Related Articles