Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

RNA polymerase in mumps virion.

J P Bernard, R L Northrop

    Journal of Virology
    |July 1, 1974
    PubMed
    Summary
    This summary is machine-generated.

    Researchers identified an RNA-dependent RNA polymerase within mumps virions. This enzyme

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    New reference charts for fetal ultrasound corpus callosum length with emphasis on the third trimester.

    Journal of gynecology obstetrics and human reproduction·2024
    Same author

    Coronal suture: ultrasonographic window of fetal cranial and brain abnormalities.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
    Same author

    Monozygotic twins discordant for 18q21.2qter deletion detected by array CGH in amniotic fluid.

    European journal of medical genetics·2013
    Same author

    Small biparietal diameter in the first trimester and pregnancy outcome.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2013
    Same author

    Oral fluid is a viable alternative for monitoring drug abuse: detection of drugs in oral fluid by liquid chromatography-tandem mass spectrometry and comparison to the results from urine samples from patients treated with Methadone or Buprenorphine.

    Journal of analytical toxicology·2011
    Same author

    Cerebral ventricle width measurements vary in relation to gestational age, fetal gender and cephalometry.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2010

    Area of Science:

    • Virology
    • Molecular Biology
    • Biochemistry

    Background:

    • Mumps is a contagious viral illness caused by the mumps virus.
    • The mumps virus belongs to the Paramyxoviridae family.
    • Understanding viral replication mechanisms is crucial for developing antiviral strategies.

    Purpose of the Study:

    • To investigate the presence and properties of polymerase activity within mumps virions.
    • To characterize the nature of the polymerase associated with the Enders' strain of mumps virus.

    Main Methods:

    • In vitro assays were performed on mumps virions (Enders' strain).
    • Polymerase activity was assessed using biochemical methods.

    Main Results:

    • An RNA-dependent RNA polymerase activity was detected in association with mumps virions.
  • The enzymatic properties of this polymerase resemble those observed in other paramyxoviruses.

    • Conclusions:

    • Mumps virions possess an intrinsic RNA-dependent RNA polymerase.
    • This finding supports the conserved replication strategies within the Paramyxoviridae family.