Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Localized conjunctival amyloidosis.

F C Blodi, D J Apple

American Journal of Ophthalmology

|September 1, 1979

Summary

This summary is machine-generated.

This study discusses a case of localized amyloidosis in the conjunctiva, mimicking cancer. While linked to rheumatoid arthritis, it was initially deemed primary, highlighting the need for systemic evaluation to rule out secondary amyloidosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prognosis in retinoblastoma: influence of histopathologic characteristics.

Journal of pediatric ophthalmology and strabismus·2014

Same author

Hydroview lens implant calcification: 186 exchanges at a district general hospital.

Eye (London, England)·2006

Same author

Suturing a tear of the anterior capsulorhexis.

The British journal of ophthalmology·2006

Same author

Linear deposits on the surfaces of intraocular lenses implanted through a hexagonal cartridge which mimic scratches/cracks on the lenses.

The British journal of ophthalmology·2005

Same author

Histology of AlphaCor skirts: evaluation of biointegration.

Cornea·2005

Same author

Calcification of modern foldable hydrogel intraocular lens designs.

Eye (London, England)·2003

Same journal

Performance of the ISOLD Score (Interleukin Score for IntraOcular Lymphoma Diagnosis) in the Diagnosis of Vitreoretinal Lymphoma in Clinical Practice.

American journal of ophthalmology·2026

Same journal

Reply to Comment on Visual Field Progression in Glaucoma Patients with Delayed Follow-Up.

American journal of ophthalmology·2026

Same journal

Comment on: "Safety and efficiency reducing retinopathy of prematurity guideline sensitivity: an external validation using a large US-based dataset".

American journal of ophthalmology·2026

Same journal

Reply to Comment on "Clinicopathological and Imaging Distinction Between Ocular Adnexal MALT Lymphoma and IgG4-Related Ophthalmic Disease".

American journal of ophthalmology·2026

Same journal

Comment on: Visual Field Progression in Glaucoma Patients With Delayed Follow-Up.

American journal of ophthalmology·2026

Same journal

Corneal sensitivity changes and nerve plexus abnormalities in noninfectious anterior uveitis.

American journal of ophthalmology·2026

See all related articles

Area of Science:

Ophthalmology
Rheumatology
Pathology

Background:

Amyloidosis is a rare condition involving abnormal protein deposits.
Rheumatoid arthritis (RA) can be associated with secondary systemic amyloidosis.
Ocular adnexal lesions can sometimes present as amyloidosis.

Observation:

A patient presented with a bulbar conjunctiva lesion resembling a tumor.
The patient had a history of severe rheumatoid arthritis.
No clear signs of systemic amyloidosis were initially observed.

Findings:

The ocular lesion was diagnosed as primary localized amyloidosis.
The diagnosis was made despite the presence of rheumatoid arthritis.
The possibility of secondary systemic amyloidosis was considered but not confirmed initially.

Related Experiment Videos

Implications:

Localized ocular amyloidosis requires careful diagnosis to differentiate from neoplastic conditions.
Patients with underlying systemic diseases like RA need thorough evaluation for potential secondary amyloidosis.
Long-term follow-up is crucial to detect early signs of systemic amyloidosis, which can be life-threatening.