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Acid phosphatase activity in human semen.

R Singer, M Sagiv, D Allalouf

    Archives of Andrology
    |January 1, 1979
    PubMed
    Summary
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    Acid phosphatase activity in human semen showed no difference between normal and abnormal samples. Tartaric acid significantly inhibited this enzyme activity by approximately 95%.

    Area of Science:

    • Biochemistry
    • Andrology
    • Enzymology

    Background:

    • Acid phosphatase is an enzyme found in human semen.
    • Its activity may be relevant in assessing seminal fluid characteristics.
    • Testosterone levels are known to influence various physiological processes, including those related to seminal fluid.

    Purpose of the Study:

    • To investigate acid phosphatase activity in normal versus abnormal human semen.
    • To determine the effect of tartaric acid on acid phosphatase activity.

    Main Methods:

    • Enzyme assays were performed on human semen samples.
    • Samples were categorized as normal or abnormal, excluding cases of testosterone deficiency.
    • The impact of tartaric acid on enzyme activity was quantified.

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    Main Results:

    • No significant differences in acid phosphatase activity were found between normal and abnormal semen samples.
    • Tartaric acid demonstrated a potent inhibitory effect, reducing enzymatic activity by approximately 95%.

    Conclusions:

    • Acid phosphatase activity levels in semen do not appear to differentiate between normal and abnormal samples in the absence of testosterone deficiency.
    • Tartaric acid is a strong inhibitor of human semen acid phosphatase, suggesting potential applications or implications in biochemical studies.