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Updated: Aug 13, 2026

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
Some new fluorescent derivatives for the mass spectrometric quantitation of biogenic amines
Abstract:
The 5-dimethyl-, diethyl-, dipropyl-, dibutyl-, and dipentyl-aminoaphghalene-1-sulfonyl (dansyl, ethanyl, propansyl, bansyl and pentansyl respectively) derivatives of tyramine and other biogenic amines were prepared and their mass spectra recorded. The relative intensity of the largest unique ion increased with increasing length of the alkyl group. Several O-alkyl-N-propansyl- and N,O-dialkyl-N-propansyl-, bansyl- and pentansyl-tyramines were also synthesized and their mass spectra recorded. Dimethylbansyl- and dimethylpentansyl-tyramines exhibited the largest unique ions in their mass spectra and the greatest sensitivity in quantitation by the integrated ion current method. Procedures for preparing these derivatives in amounts ranging from nanograms to milligrams are presented and their thin-layer chromatographic behavior in three solvent systems is described.
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