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Pleomorphic virus-like particles in human faeces.

M Mathan, V I Mathan, S P Swaminathan

    Lancet (London, England)
    |May 10, 1975
    PubMed
    Summary
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    Pleomorphic, fringed particles resembling viruses were found in 90% of stools from South Indian children and adults, but not newborns. This discovery may link to common intestinal issues in the region.

    Area of Science:

    • Virology
    • Gastroenterology
    • Public Health

    Background:

    • Intestinal abnormalities are prevalent in certain regions of India.
    • Viral infections can cause significant gastrointestinal distress.

    Purpose of the Study:

    • To investigate the presence of novel viral particles in fecal samples from South Indian populations.
    • To explore potential correlations between observed particles and regional intestinal health issues.

    Main Methods:

    • Electron microscopy was used to examine stool samples.
    • Samples were collected from children, adults, and neonates in South India.

    Main Results:

    • Pleomorphic, fringed particles were detected in 90% of stool samples from children and adults.

    Related Experiment Videos

  • No such particles were observed in stool samples from neonates.
  • Conclusions:

    • The presence of these unique viral-like particles in a high percentage of the population warrants further investigation.
    • A potential link exists between these particles and the common intestinal abnormalities found in this region of India.