[Pharmacological properties of a new benzimidazole derivative]

The pharmacological action of the new benziamidazole derivative 1-(3-diethylamino-2-oxypropyl)-2-propylbenzimidazole (abazol) was studied in experiments on mice, dogs, cats and isolated ears of rabbits. In cats and dogs, abazol produces a hypotensive effect and transient reduction of the EEG wave amplitude. Abazol dilates the vessels of an isolated rabbit ear. It shows less toxicity and less pronounced convulsant effect as compared to dibazol.