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Radio-opaque pellets as faecal markers for faecal fat estimation in malabsorption.
Gut
|July 1, 1979
Summary
Radio-opaque pellets (ROP) offer a precise and simple method for fecal fat studies. These markers are suitable for routine use, showing advantages over current methods in malabsorption investigations.
Area of Science:
- Gastroenterology
- Clinical Nutrition
- Medical Diagnostics
Background:
- Malabsorption investigations require accurate fecal markers.
- Current markers like polyethylene glycol (PEG) and chromic oxide have limitations.
- Radio-opaque pellets (ROP) were evaluated as an alternative fecal marker.
Purpose of the Study:
- To compare the efficacy of radio-opaque pellets (ROP) with polyethylene glycol (PEG) and chromic oxide as fecal markers.
- To assess the suitability of ROP for routine fecal fat studies.
- To determine if ROP-corrected fecal fat results correlate with PEG- and chromic oxide-corrected results.
Main Methods:
- Thirty-seven patients undergoing malabsorption investigation were enrolled.
- Radio-opaque pellets (ROP) were administered and compared with PEG and chromic oxide as continuous fecal markers.
- Percentage recovery of all markers was analyzed.
- Faecal fat was corrected using ROP, PEG, and chromic oxide.
Main Results:
- Percentage recovery of all markers exhibited a wide range but were similar.
- ROP-corrected daily fecal fat correlated very closely with PEG- and chromic oxide-corrected fat results.
- Estimation of ROP was found to be precise and simple, minimizing fecal handling.
Conclusions:
- Radio-opaque pellets (ROP) are suitable for routine use in fecal fat studies.
- ROP offer advantages over currently used fecal markers.
- ROP provide a precise, simple, and efficient method for malabsorption investigations.
