Postoperative thrombosis in Thai women

Area of Science:

• Vascular Surgery
• Gynecologic Oncology
• Thrombosis Research

Background:

• Deep-vein thrombosis (D.V.T.) is a significant postoperative complication.
• Incidence rates of D.V.T. can vary geographically and by patient demographics.
• Previous studies suggest potential differences in D.V.T. prevalence between Asian and Western populations.

Purpose of the Study:

• To determine the incidence of postoperative D.V.T. in Thai women undergoing abdominal hysterectomy for benign conditions or major pelvic surgery for gynecologic malignancies.
• To compare the D.V.T. rates in Thai women with those reported in a similar study conducted in England.

Main Methods:

• Utilized 125-I-labelled fibrinogen infusion test and phlebography to detect D.V.T.
• Studied 117 Thai women with benign conditions and 52 with gynecologic malignancies.
• Compared findings with an identical study performed in Oxford, England.

Main Results:

• D.V.T. was detected in 1.7% of Thai women with benign conditions and 3.8% with malignant diseases.
• D.V.T. incidence was significantly lower in Thai women compared to English women (12% benign, 35% malignant).

Conclusions:

• Postoperative D.V.T. is significantly less common in Thai women undergoing gynecologic surgery compared to women in England.
• Further research may explore genetic or environmental factors contributing to this observed difference in D.V.T. incidence.