Related Experiment Video
Updated: Aug 18, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Post-traumatic middle cerebral artery thrombosis
Abstract:
Post-traumatic thrombosis of the middle cerebral artery (MCA) is uncommon: only 39 cases were found in the literature. In the present report, eight cases of post-traumatic MCA thrombosis are analyzed and compared with other reported cases. The symptoms can be easily confused with those of expanding intracranial hematoma. Although ancillary noninvasive diagnostic methods are helpful, cerebral angiography confirms the diagnosis. The morbidity and mortality rates are high, and treatment has been mainly supportive. The low mortality in the present study may be related to the absence of severe head or other trauma. Possible cerebral revascularization procedures are also discussed.
Insights
Post-traumatic middle cerebral artery (MCA) thrombosis is rare but serious. Early diagnosis via angiography is crucial, as symptoms mimic intracranial hematoma, and outcomes are often poor.
Area of Science:
- Neurology
- Vascular Surgery
- Trauma Surgery
Background:
- Post-traumatic thrombosis of the middle cerebral artery (MCA) is an uncommon yet significant complication.
- Literature review reveals only 39 reported cases prior to this study.
- Symptoms can be misdiagnosed as expanding intracranial hematoma, complicating timely intervention.
Purpose of the Study:
- To analyze eight new cases of post-traumatic MCA thrombosis.
- To compare these cases with previously reported instances in the literature.
- To discuss diagnostic modalities, treatment strategies, and potential revascularization procedures.
Main Methods:
- Retrospective analysis of eight patients with post-traumatic MCA thrombosis.
- Comparison with a literature review of 39 previously reported cases.
- Evaluation of diagnostic methods, including noninvasive techniques and cerebral angiography.
Main Results:
- Eight new cases of post-traumatic MCA thrombosis were identified and analyzed.
- Cerebral angiography was confirmed as the definitive diagnostic tool.
- The study observed a lower mortality rate compared to previous reports, potentially due to less severe associated trauma.
Conclusions:
- Post-traumatic MCA thrombosis requires high clinical suspicion due to overlapping symptoms with intracranial hematoma.
- While noninvasive methods offer supportive diagnostic information, cerebral angiography remains essential for confirmation.
- Management is primarily supportive, but potential revascularization procedures warrant further investigation, especially in less severe trauma cases.
Related Concept Videos
Stroke: Introduction and Types
Transient Ischemic Attack l: Introduction

