[In-vitro motility studies on the strips of the human gallbladder (author's transl)]

Studies in-vitro motility of the human gallbladder was investigated in the longitudinally cut strips obtained from 24 patients. Strips of the wall of the organ, containing mucosa, muscle and serosa, 5 mm in width and 15 mm in length, were cut from the fundus, body and neck. These specimens were suspended in Tyrode solution at 36 degrees C equilibrated with the 100% O2. Recordings were made on a pen chart recorder which were transduced using a isometric system by the changes of contractions. The results obtained were as follows: 1. The strips from three parts of the gallbladder showed rhythmic and tonic spontaneous contractions. 2. The tonic contractions from fundus were strongest in those three. 3. The rhythmic contractions of neck exhibited greater amplitude than those of fundus and body.