Primary reticulum-cell sarcoma of bone in Western India

Thirty-five cases of primary reticulum-cell sarcoma seen during 28 years are presented.These tumours occurred five times more frequently in males than in females, and were seen most commonly in adults. The femur was the commonest location. None of the tumours was located in the small bones of the hand, foot or skull bones (excluding maxilla).Radiation therapy has been the treatment of choice. Though the initial response was good, local recurrence and metastasis to regional nodes and generalised dissemination was not uncommon. Radiation therapy to regional nodes and concomitant chemotherapy are suggested to prevent metastasis in regional nodes and generalised dissemination.These tumours were found to have a spectrum of activity varying from a rapid fatal outcome within a few months to survival for many years.