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Isolation, Identification, and Purification of Murine Thymic Epithelial Cells
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Antigen-binding cells in normal mouse thymus

F Modabber, S Morikawa, A H Coons

    Science (New York, N.Y.)
    |December 4, 1970
    PubMed

    The thymus of a normal adult mouse contains lymphocytic cells with a large number of antigen-binding receptors. Binding of the antigen by these cells is specific and can be inhibited by cross-reactive materials. It is possible that the interaction of thymocytes with antibody-forming precursor cells, required in the primary immune response to certain antigens, is mediated by these specific antigen-binding cells of the thymus.

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