Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A two-year experience with human heart transplantation.

R B Griepp, E B Stinson, D A Clark

    California Medicine
    |August 1, 1970
    PubMed
    Summary

    Cardiac transplantation shows promise for severe heart failure patients, offering improved survival and return to activity. However, infection and rejection remain significant challenges in this early clinical study.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The health department and medical care; group practice in preventive medicine.

    American journal of public health and the nation's health·2010
    Same author

    The prognosis of fasciectomy for abductor digiti minimi and pretendinous cords in Dupuytren's disease of the little finger.

    Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·2010
    Same author

    Effects of reduced frequency of milk removal on gene expression in the bovine mammary gland.

    Physiological genomics·2009
    Same author

    DISCUSSION ON THE TREATMENT BY PHYSICAL METHODS OF MEDICAL DISABILITIES INDUCED BY THE WAR.

    Proceedings of the Royal Society of Medicine·2009
    Same author

    Effect of using a stand-off pad on Campylobacter jejuni strain diversity in a herd of dairy cows.

    Letters in applied microbiology·2009
    Same author

    Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI.

    Neurology·2009

    Area of Science:

    • Cardiology
    • Surgical Innovation

    Background:

    • Early clinical application of cardiac transplantation at Stanford.
    • Translation of laboratory techniques to patient care.

    Purpose of the Study:

    • To evaluate the feasibility and outcomes of early clinical cardiac transplantation.
    • Define operative indications and manage post-transplant complications.

    Main Methods:

    • Performed cardiac transplantation on 20 patients.
    • Focused on operative technique, rejection diagnosis, and treatment.

    Main Results:

    • Achieved 6-month survival of 42% and 1-year survival of 35%.
    • Identified infection and rejection (acute and chronic) as major challenges.
    • Demonstrated improved survival compared to patients awaiting transplants.

    Conclusions:

    • Cardiac transplantation offers a viable option for severe heart failure patients unresponsive to other therapies.
    • Continued research is needed to overcome challenges in infection and rejection management.

    Related Experiment Videos