Resistant transitory epilepsy in children

Three case histories are presented which are characterized by progressive, severe symptoms of mental and epileptic nature with EEG abnormalities of increasing severity culminating in "hypsarhythmia". The seizures were resistant to any treatment over a period of several months. Apparently spontaneous cures followed, and the patients remained healthy during follow-up, which ranged from 10 to 12 years. The observations confirm Lennox's remark that a miraculous cure may occasionally be expected in even severe, probably symptomatic, epilepsy. Some exogenous (infectious?) cause is suspected.