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Related Experiment Videos

Motor events in equine large colon.

A F Sellers, J E Lowe, J Brondum

    The American Journal of Physiology
    |November 1, 1979
    PubMed
    Summary

    The equine large colon

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    Area of Science:

    • Equine gastrointestinal physiology
    • Colonic motility research
    • Digestive system function in horses

    Background:

    • The equine large colon is crucial for cellulose fermentation.
    • Understanding colonic function is key to equine health.
    • Specific regions may regulate digesta flow.

    Purpose of the Study:

    • To characterize the juncture area of the equine large colon's ventral and dorsal divisions.
    • To investigate its role as a pacemaker and in reservoir function.
    • To assess the impact of feeding and nerve supply on colonic pressure.

    Main Methods:

    • In vivo studies in 13 chronic unanesthetized horses.
    • In vitro analysis of 25 colonic preparations.
    • Measurement of intraluminal pressure and electrical stimulation.

    Main Results:

    • The juncture area exhibits resistance to aboral flow, suggesting a pacemaker function.
    • Feeding increased intraluminal pressure peaks, unaffected by extrinsic nerve resection.
    • Electrical stimulation mimicked feeding-induced pressure patterns.

    Conclusions:

    • The equine large colon juncture acts as a pacemaker, aiding reservoir function.
    • Colonic pressure regulation involves intrinsic mechanisms, with extrinsic nerves playing a modulatory role.
    • This area is vital for regulating digesta passage and pressure dynamics.

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