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Summary
Hyperprolactinemia has minor significance in male infertility and impotence. However, measuring human prolactin (hPRL) is crucial for hypogonadotropic hypogonadism, loss of libido, or impotence to detect pituitary adenomas.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Urology
Background:
- Hyperprolactinemia, elevated human prolactin (hPRL) levels, can affect reproductive health.
- Its role in male infertility and impotence requires further clarification.
Purpose of the Study:
- To investigate the significance of hyperprolactinemia in male infertility and impotence.
- To explore correlations between hPRL and other reproductive hormones and sperm parameters.
Main Methods:
- Assessed hPRL levels in patients with male infertility and impotence.
- Correlated hPRL with testosterone, luteinizing hormone (hLH), follicle-stimulating hormone (hFSH), sperm count, and motility.
Main Results:
- Hyperprolactinemia was detected in only 2/71 infertile men and 0/53 impotent men.
- A weak negative correlation was observed between hPRL and testosterone in oligozoospermic men.
- No significant correlations were found between hPRL and hLH, hFSH, sperm count, or motility.
Conclusions:
- Hyperprolactinemia is of minor significance in most cases of male infertility and impotence.
- hPRL measurement is recommended for patients with hypogonadotropic hypogonadism, loss of libido, or impotence to rule out pituitary adenomas.