Ocular and orbital metastatic carcinoma

Area of Science:

• Ophthalmology
• Oncology
• Pathology

Background:

• Metastatic carcinoma to the eye and orbit represents a significant clinical challenge.
• Understanding the primary sources and common sites of ocular metastasis is crucial for patient management.

Purpose of the Study:

• To review cases of metastatic carcinoma involving the eye and orbit.
• To identify demographic data, primary cancer types, and common metastatic locations.

Main Methods:

• Retrospective review of 100 cases of metastatic carcinoma to the eye and orbit.
• Analysis of patient demographics, primary tumor origins, and sites of metastasis.

Main Results:

• The study included 100 patients (59 female, 35 male).
• Average age was 60 for females and 52 for males.
• Breast carcinoma was the most common primary in females; lung carcinoma in males.
• The left eye and orbit were more frequently involved (30 vs. 27 cases).
• The choroid and orbit were the most common sites of metastasis.

Conclusions:

• Ocular and orbital metastases are more common in women, often originating from breast cancer.
• Lung carcinoma is a frequent primary source in men.
• The choroid and orbit are primary targets for metastatic spread.