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Membrane vs bubble oxygenators: a prospective study of 52 patients
Archives of Surgery (Chicago, Ill. : 1960)
|November 1, 1979
Summary
This study compared two oxygenators for cardiopulmonary bypass in coronary bypass surgery. Both the Q-100 and Travenol Membrane Oxygenator (TMO) performed adequately, with similar clinical outcomes and blood parameters.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Medical Device Technology
Background:
- Ongoing debate regarding the optimal oxygenator for cardiopulmonary bypass (CPB).
- Need for comparative clinical data on different oxygenator models.
Purpose of the Study:
- To prospectively compare the performance and clinical outcomes of the Q-100 and Travenol Membrane Oxygenator (TMO) during coronary bypass surgery.
Main Methods:
- Prospective study involving 52 patients undergoing coronary bypass surgery.
- Alternating use of Q-100 and TMO oxygenators between cases.
- Monitoring of CPB oxygen flow, blood gas levels, coagulation parameters, blood loss, platelet reduction, and postoperative complications.
Main Results:
- Q-100 required higher oxygen flow, but PO2 levels were similar between groups.
- Identical heparin dosage, clotting times, bleeding, and platelet reduction.
- Similar postoperative complications, with one myocardial infarction and one neurological issue in the Q-100 group, and one neurological issue in the TMO group.
- Lower blood trauma (plasma hemoglobin) observed with the TMO.
Conclusions:
- Both Q-100 and TMO oxygenators demonstrated adequate clinical performance in open-heart surgery.
- The TMO showed less blood trauma but had a longer setup time and higher cost.
- Clinical choice may depend on specific institutional priorities regarding cost, setup, and blood trauma minimization.