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[Systemic hemangioendotheliomatosis].

E A Dikshteĭn, M I Reĭderman, M N Lysenko

    Arkhiv Patologii
    |January 1, 1979
    PubMed
    Summary

    A rare systemic hemangioendotheliomatosis case in a 53-year-old female involved multiple organs. Treatment offered temporary improvement, but the patient succumbed to complications.

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    Area of Science:

    • Oncology
    • Pathology
    • Hematology

    Background:

    • Systemic hemangioendotheliomatosis is a rare vascular tumor.
    • This case presents a rare occurrence involving multiple organs.

    Observation:

    • A 53-year-old female patient presented with systemic hemangioendotheliomatosis.
    • Involvement included skin, lymph nodes, spleen, liver, bone marrow, and lungs.
    • Histopathology revealed intra- and extra-vascular endothelial proliferation.

    Findings:

    • Cytostatic therapy led to short-term improvement, including tumor node regression and cicatrization.
    • A significant lymphoplasmocytic reaction was noted.
    • The patient developed cachexia, anemia, and leukopenia.

    Implications:

    • This case highlights the aggressive nature of systemic hemangioendotheliomatosis.
    • It underscores the challenges in managing this rare condition.
    • Understanding the pathological response to therapy is crucial for future treatment strategies.

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