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Dengue virus isolation in Indonesia, 1975-1978
Asian Journal of Infectious Diseases
|March 1, 1979
Summary
Dengue virus serotypes 1-4 were endemic in Indonesia between 1975-1978. Dengue 3 was the most common and widespread serotype identified in patients across the country.
Area of Science:
- Medical Entomology
- Virology
- Infectious Diseases
Background:
- Dengue hemorrhagic fever (DHF) is a significant public health concern in tropical regions.
- Understanding the epidemiology of dengue virus serotypes is crucial for disease control.
Purpose of the Study:
- To report virus isolations from dengue hemorrhagic fever patients in Indonesia from 1975 to 1978.
- To identify the predominant and most widely distributed dengue virus serotype in Indonesia during the study period.
Main Methods:
- Virus isolation from clinical samples of DHF patients.
- Serotyping of isolated dengue viruses.
- Mosquito inoculation technique for virus isolation.
Main Results:
- All four dengue virus serotypes (1, 2, 3, and 4) were found to be endemic in Jakarta.
- Dengue serotype 3 was the predominant virus isolated from patients in Jakarta.
- Dengue serotype 3 was also the most frequently isolated virus outside Jakarta and showed the widest geographical distribution within Indonesia.
Conclusions:
- Dengue virus serotype 3 was the most prevalent and widely distributed serotype in Indonesia between 1975 and 1978.
- The findings highlight the epidemiological importance of dengue serotype 3 in the region.
- The study discusses the sensitivity of the mosquito inoculation technique for dengue virus isolation.