Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity

Subchronic treatment with phencyclidine in adolescence leads to impaired exploratory behavior in adult rats without altering social interaction or N-methyl-D-aspartate receptor binding levels.

Journal of neuroscience research·2014

Agonist-induced desensitization of 5-HT(2) receptors on cultured calf aortic smooth muscle cells.

Neurochemistry international·2009

Effects of lesions on (3)H-apomorphine and (3)H-spiperone stereospecific binding sites in subcellular fractions of rat striatum.

Neurochemistry international·2009

Synthesis and biodistribution of [11C]R107474, a new radiolabeled alpha2-adrenoceptor antagonist.

Bioorganic & medicinal chemistry·2006

Bilateral control of brain activity by dopamine D1 receptors: evidence from induction patterns of regulator of G protein signaling 2 and c-fos mRNA in D1-challenged hemiparkinsonian rats.

Neuroscience·2005

Synthesis and biodistribution of [(11)C]R116301, a promising PET ligand for central NK(1) receptors.

Bioorganic & medicinal chemistry·2005

AXL drives immunotherapy resistance by modulating IL-17 in bladder cancer.

Biochemical pharmacology·2026

Nab-paclitaxel exacerbates PD-1 antibody-associated immune myocarditis via the STAT1/Egr-1/Trp53-mediated ferroptosis pathway.

Biochemical pharmacology·2026

Macrophage-intrinsic STAT3 drives LPS-induced acute lung injury: allosteric blockade by K116 and genetic validation via conditional knockout.

Biochemical pharmacology·2026

PARP1-targeting PROTAC attenuates alcohol-associated liver injury and ileal epithelial damage.

Biochemical pharmacology·2026

Celastrol induces mitochondrial apoptosis in hepatocellular carcinoma by suppressing LRP6-associated Wnt/β-catenin signaling.

Biochemical pharmacology·2026

Zinc gluconate attenuates oxaliplatin-induced pulmonary injury via suppressing the TLR4/NF-κB signaling.

Biochemical pharmacology·2026

A Proposal for the Use of an Innovative Two-Stage PK-Clinical Adaptive Trial in Biosimilar Product Development.

The AAPS journal·2026

Performance of large language models on narrow therapeutic index drug monitoring: Implications for clinical pharmacy practice.

Journal of the American Pharmacists Association : JAPhA·2026

Solid Modification Strategies for Active Pharmaceutical Ingredients (APIs): A Systematic Review on Approaches, Improvements, and Limitations.

Pharmaceutical development and technology·2026

A comparative QbD-driven optimization of solid lipid nanoparticles and nanostructured lipid carriers for enhanced drug delivery.

Biochemical and biophysical research communications·2026

A novel in vitro permeability and efflux classification system for proteolysis targeting chimeras.

Drug metabolism and disposition: the biological fate of chemicals·2026

Peptides in Plastic Surgery: Promise, Evidence, and Pitfalls.

Annals of plastic surgery·2026

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Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity

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Subchronic treatment with phencyclidine in adolescence leads to impaired exploratory behavior in adult rats without altering social interaction or N-methyl-D-aspartate receptor binding levels.

Agonist-induced desensitization of 5-HT(2) receptors on cultured calf aortic smooth muscle cells.

Effects of lesions on (3)H-apomorphine and (3)H-spiperone stereospecific binding sites in subcellular fractions of rat striatum.

Synthesis and biodistribution of [11C]R107474, a new radiolabeled alpha2-adrenoceptor antagonist.

Bilateral control of brain activity by dopamine D1 receptors: evidence from induction patterns of regulator of G protein signaling 2 and c-fos mRNA in D1-challenged hemiparkinsonian rats.

Synthesis and biodistribution of [(11)C]R116301, a promising PET ligand for central NK(1) receptors.

AXL drives immunotherapy resistance by modulating IL-17 in bladder cancer.

Nab-paclitaxel exacerbates PD-1 antibody-associated immune myocarditis via the STAT1/Egr-1/Trp53-mediated ferroptosis pathway.

Macrophage-intrinsic STAT3 drives LPS-induced acute lung injury: allosteric blockade by K116 and genetic validation via conditional knockout.

PARP1-targeting PROTAC attenuates alcohol-associated liver injury and ileal epithelial damage.

Celastrol induces mitochondrial apoptosis in hepatocellular carcinoma by suppressing LRP6-associated Wnt/β-catenin signaling.

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A comparative QbD-driven optimization of solid lipid nanoparticles and nanostructured lipid carriers for enhanced drug delivery.

A novel in vitro permeability and efflux classification system for proteolysis targeting chimeras.

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Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity

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