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Simultaneous quantitative estimates of several isotopically labelled substances in the picogram range with selected
Biomedical Mass Spectrometry
|August 1, 1979
Abstract:
The use of a model developed by the authors for the simultaneous quantitative determination of several isotopically labelled substances of the same chemical structure is described in detail for a two substance system. A computational flow chart is included. An example using natural estradiol and 4-[14C] labelled estradiol with manifold deuterated estradiol as an internal standard is presented. The basis of the model is discussed.