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Sulfadiazine susceptibility patterns of Neissera meningitidis group Y

C J Oughton, J A Robinson, W E Meekins

    Applied Microbiology
    |December 1, 1969
    PubMed

    Insights

    Four of 46 Neisseria meningitidis group Y strains showed resistance to sulfadiazine. This highlights potential challenges in treating infections caused by this specific bacterial strain.

    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Antimicrobial Resistance

    Background:

    • Neisseria meningitidis is a significant bacterial pathogen.
    • Group Y strains are a common cause of meningococcal disease.
    • Sulfadiazine is an antibiotic used to treat bacterial infections.

    Purpose of the Study:

    • To determine the susceptibility of Neisseria meningitidis group Y strains to sulfadiazine.
    • To identify the prevalence of sulfadiazine resistance in this bacterial population.

    Main Methods:

    • Agar plate-dilution technique was employed.
    • 46 Neisseria meningitidis group Y strains were tested.
    • Resistance was assessed against a specific concentration of sulfadiazine (1.0 mg/100 ml).

    Main Results:

    • Four out of 46 strains (8.6%) exhibited resistance to sulfadiazine.
    • A notable percentage of Neisseria meningitidis group Y strains were found to be resistant.

    Conclusions:

    • A proportion of Neisseria meningitidis group Y strains possess resistance to sulfadiazine.
    • This finding has implications for the effective treatment of infections caused by these strains.

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