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Updated: Sep 7, 2026

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Mouse Models of Periventricular Leukomalacia
Published on: May 19, 2010
Cerebellar hypoplasia in neonatal rats caused by lymphocytic choriomeningitis virus
Abstract:
Lymphocytic choriomeningitis virus, strain E-350, when inoculated intracerebrally in rats 1 to 7 days old, produces an acute destructive infection of the cerebellar cortex resulting in permanent cerebellar hypoplasia and ataxia. Several other arenoviruses may produce a similar lesion in neonatal rodents.
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