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[Effect of preparations on the capacity of thyroxine to suppress compensatory thyroid hypertrophy in rats]
Farmakologiia I Toksikologiia
|November 1, 1979
Abstract:
It has been shown in compensatory hypertrophy of the thyroid gland of male rats weighing 180--240 g that of 18 compounds tested five drugs (cyclic AMP, theophylline, phenformin, tryptophan and disulfiram) reduce an inhibitory effect of thyroxin and are likely to raise the threshold of homeostatic inhibition in the hypothalamohypophyseal and thyroid system.