Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

Endoscopic Procedures II: Colonoscopy

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:

Endoscopic Procedures III: Video Capsule Endoscopy

Endoscopic Procedures III: Video Capsule Endoscopy

Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Easy clip to treat anal fistula tracts: a word of caution.

International journal of colorectal disease·2015

Same author

Fracture incidence after 3 years of aromatase inhibitor therapy.

Annals of oncology : official journal of the European Society for Medical Oncology·2014

Same author

[Thoraco-abdominal aortitis in ankylosing spondylitis: a case report and review of literature].

Journal des maladies vasculaires·2011

Same author

[Turcot syndrome: a case report].

Journal de radiologie·2009

Same author

[Childhood drug policy in France and Europe: questions and problems].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2009

Same author

[Collective intoxication with "mad honey" on Reunion Island].

Bulletin de la Societe de pathologie exotique (1990)·2009

Same journal

How important is fiber in the Crohn's disease story?

Gastroenterology·2026

Same journal

Reply to "Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy".

Gastroenterology·2026

Same journal

Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy.

Gastroenterology·2026

Same journal

A High-Risk Impaction: To Scope or to Stent First?

Gastroenterology·2026

Same journal

Epithelial FOXP3 orchestrates O-glycosylated IL-6 secretion to drive pancreatic fibrocarcinogenesis.

Gastroenterology·2026

Same journal

Reply to "Methodological Considerations on Neonatal Metabolomics and Future Inflammatory Bowel Disease".

Gastroenterology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 5, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 17, 2013

Fatal colonic explosion during colonoscopic polypectomy.

M A Bigard, P Gaucher, C Lassalle

Gastroenterology

|December 1, 1979

Summary

This summary is machine-generated.

A rare colonic explosion during colonoscopic polypectomy led to fatal hemorrhage. This case highlights risks associated with mannitol bowel prep and electrocautery, suggesting safer alternatives.

More Related Videos

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Related Experiment Videos

Last Updated: May 5, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 17, 2013

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Area of Science:

Gastroenterology
Surgical Safety

Background:

Colonoscopic polypectomy is a common procedure for polyp removal.
Bowel preparation is essential for clear visualization during colonoscopy.

Observation:

A patient experienced a colonic explosion during snare removal of a cecal polyp.
High-frequency current was used for polyp removal.
Mannitol solution was used for bowel preparation.

Findings:

The explosion resulted in uncontrollable hemorrhage.
The patient died despite emergency surgery and extensive blood transfusion.
This represents the first reported case of colonic explosion during polypectomy.

Implications:

Routine use of carbon dioxide insufflation during polypectomy is recommended.
Avoidance of mannitol for bowel preparation is suggested to prevent similar incidents.
Enhanced safety protocols for colonoscopic procedures may be necessary.