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Related Experiment Videos

Small bowel in typhoid fever.

H K Chuttani, K Jain, R C Misra

    Gut
    |September 1, 1971
    PubMed
    Summary
    This summary is machine-generated.

    Salmonellosis, including typhoid fever, causes temporary small bowel dysfunction in most patients. Intestinal function and morphology largely recover quickly after acute illness, indicating mild residual effects.

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    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Microbiology

    Background:

    • Typhoid and paratyphoid fever are significant public health concerns.
    • Salmonellosis can impact gastrointestinal function.
    • Understanding post-illness recovery is crucial for patient management.

    Purpose of the Study:

    • To evaluate the residual functional and morphological status of the small bowel after recovery from typhoid and paratyphoid fever.
    • To assess the extent and duration of intestinal impairment following salmonellosis.

    Main Methods:

    • Intestinal function tests including faecal fat and D-xylose absorption were performed.
    • Jejunal biopsies were conducted to assess small bowel morphology.
    • Tests were administered to patients shortly after recovery from acute salmonellosis.

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    Main Results:

    • Nearly 50% of patients (14/29) exhibited impaired D-xylose absorption, which resolved rapidly.
    • No instances of steatorrhoea (fat malabsorption) were observed.
    • Jejunal biopsies revealed increased chronic inflammatory cell infiltration in 8 out of 22 patients, without specific pathological lesions.

    Conclusions:

    • Intestinal injury from salmonellosis typically results in mild, transient functional disturbances of the small bowel.
    • The small intestine demonstrates a capacity for rapid functional and morphological recovery after typhoid and paratyphoid fever.