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Updated: Mar 25, 2026

An Ex vivo Mast Cell Degranulation Assay using Crude Peritoneal Exudate Cells and Natural Antigen Stimulation
Published on: April 27, 2021
[Allergic reactions following dextrane infusions (author's transl)]
Abstract:
14 allergic reactions to dextran 60 and dextran 75 are reported. In 8 patients the peripheral pulse became impalpable; Medical history and clinical examination did not reveal any predisposition. Histamine liberation is to be discussed. Antihistamines did not protect against allergic reactions of colloid plasma expanders. All the patients were treated with prednisolone and fluids. After rapid infusion of Ringer-lactate and plasma protein solution to an amount of 2000-2775 ml adequate circulation was restored.
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