The time scale of tooth development and replacement in Xenopus laevis (Daudin)

One hundred and seventy two larval specimens of Xenopus laevis were reared in such a way that their rates of development (as measured by external criteria) were similar, and so the course of dental development could be examined histologically in a cross sectional study. In this way the events of tooth development were observed, and a time scale constructed for these events. The teeth took an average time of 26 days to develop, erupt and become ankylosed to the bony pedestal, after which each tooth was in a functional position for only about 7 days. Individual tooth replacement was assessed to occur about every 16 days. By comparing the number and size of the odontoblasts responsible for dentinogenesis in 18 months old adult Xenopus laevis with the odontoblasts in the larval specimens, the conclusion was drawn that, despite the larger size of the adult teeth, the time involved in their development and replacement may well be of similar duration to the smaller larval teeth. The significance of the findings for the Zahnreihen Theory is discussed.