Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Identification of enterotoxin E.

M S Bergdoll, C R Borja, R N Robbins

    Infection and Immunity
    |November 1, 1971
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Generating fair, reliable, and accurate neuropsychological test norms for people with HIV in a low- or middle-income country.

    Journal of neurovirology·2024
    Same author

    Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa.

    AIDS research and therapy·2023
    Same author

    Measuring ART Adherence Among Young Adults with Perinatally Acquired HIV: Comparison Between Self-report, Telephone-Based Pill Count, and Objective Pharmacologic Measures.

    AIDS and behavior·2023
    Same author

    Construct Validity Supports Use of a Novel, Tablet-Based Neurocognitive Assessment for Adolescents and Young Adults Affected by Perinatal HIV from Vulnerable Communities in the United States.

    AIDS and behavior·2020
    Same author

    The Impact of HIV-Associated Neurocognitive Impairment on Driving Performance in Commercial Truck Drivers.

    AIDS and behavior·2020
    Same author

    Microbiological Quality of Tofu and Related Products in Canada.

    Journal of food protection·2019
    Same journal

    The cholesterol-dependent cytolysin promotes <i>Streptococcus</i> systemic spread and induces arachidonic acid accumulation-mediated lethality in a murine intraperitoneal infection model.

    Infection and immunity·2026
    Same journal

    Phenotypic and genotypic analysis of <i>Candida albicans</i> vaginal isolates reveals that <i>ECE1</i> expression underpins pathogenicity.

    Infection and immunity·2026
    Same journal

    <i>Staphylococcus aureus</i> pore-forming toxins differentially shape disease severity in experimental endophthalmitis.

    Infection and immunity·2026
    Same journal

    Group B streptococcal membrane vesicles induce proinflammatory responses in neonatal meninges.

    Infection and immunity·2026
    Same journal

    <i>Pseudomonas aeruginosa</i> infection causes lysosomal dysfunction in the cystic fibrosis bronchial epithelium.

    Infection and immunity·2026
    Same journal

    The role of probiotics in restoring and maintaining vaginal microbiome health: a review.

    Infection and immunity·2026
    See all related articles

    Researchers identified a new staphylococcal enterotoxin, designated enterotoxin E. This discovery was made by purifying the toxin and developing a specific antitoxin, confirming its unique properties.

    Area of Science:

    • Microbiology
    • Immunology
    • Toxicology

    Background:

    • Staphylococcal infections can produce various toxins.
    • Enterotoxins are a significant class of staphylococcal toxins responsible for food poisoning.
    • Previous research identified several staphylococcal enterotoxins, but the full spectrum was not characterized.

    Purpose of the Study:

    • To identify and characterize a novel enterotoxin produced by Staphylococcus.
    • To confirm the toxic properties and specificity of the newly identified enterotoxin.

    Main Methods:

    • Purification of the enterotoxin from staphylococcal strain FRI-326.
    • Preparation of a specific antitoxin against the purified enterotoxin.
    • Determination of enterotoxin toxicity in rhesus monkeys.

    Related Experiment Videos

  • Assessment of enterotoxin-antitoxin reaction specificity using gel diffusion assays.
  • Main Results:

    • A new enterotoxin was successfully purified from Staphylococcus strain FRI-326.
    • The purified substance demonstrated toxicity in vivo (rhesus monkeys).
    • Specific antitoxin confirmed the unique identity and specificity of the enterotoxin, which was designated enterotoxin E.

    Conclusions:

    • A previously unidentified staphylococcal enterotoxin, enterotoxin E, has been discovered.
    • Enterotoxin E possesses toxic properties and can be specifically identified by its corresponding antitoxin.
    • This finding expands the known repertoire of staphylococcal enterotoxins and aids in understanding staphylococcal pathogenicity.