Metabolic activation of N-hydroxy compounds by conjugation

Changes in aldehyde dehydrogenase during rat urinary bladder carcinogenesis.

Carcinogenesis·1989

Oxidation of N-butyl-N-(3-formylpropyl)nitrosamine to N-butyl-N-(3-carboxypropyl)nitrosamine in rat liver and inhibition by disulfiram.

Carcinogenesis·1988

Inhibition of DNA methylase activity by acrolein.

Carcinogenesis·1988

Influence of disulfiram on the metabolism of the urinary bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine in the rat.

Carcinogenesis·1987

Induction of repair synthesis of DNA in primary cultures of rat urothelial cells by derivatives of the bladder carcinogen, N-n-butyl-N-(4-hydroxybutyl)nitrosamine.

Chemico-biological interactions·1985

Comparative carcinogenicity of N-butyl-N-(3-carboxypropyl)-nitrosamine and N-butyl-N-(4-hydroxybutyl)nitrosamine for the urinary bladder of (C57BL/6 X DBA/2)F1 mice.

Journal of the National Cancer Institute·1984

Inhibiting CYP2A5 enzyme in mice decreases circulating cotinine after nicotine administration and increases dopamine in the brain.

Xenobiotica; the fate of foreign compounds in biological systems·2026

Leucoseptoside a reverses multidrug resistance in breast cancer cells by targeting P-glycoprotein (P-gp/ABCB1) transporter.

Xenobiotica; the fate of foreign compounds in biological systems·2026

Oxycodone Alleviates Post-anesthesia Cognitive Impairment in the Elderly via miR-150-5p/H731 axis.

Xenobiotica; the fate of foreign compounds in biological systems·2026

In vitro and in vivo intestinal and hepatic oxidative metabolism of typical cytochrome P450 3A substrates, midazolam, nifedipine, and quinidine, in minipigs: a comparison with humans, monkeys, and dogs.

Xenobiotica; the fate of foreign compounds in biological systems·2026

Formaldehyde directly induces cytotoxicity in human lymphocytes through ROS formation, mitochondrial/lysosomal destruction and oxidative stress; analysis of the protective effects of crocin.

Xenobiotica; the fate of foreign compounds in biological systems·2026

An LC-MS/MS method for simultaneous quantification of six components of Angelicae pubescentis radix and systematic evaluation of Angelicae pubescentis radix as a potential inhibitor of multiple cytochrome P450 enzymes.

Xenobiotica; the fate of foreign compounds in biological systems·2026

Total Synthesis of (±)-Caryopincaolide A.

Organic letters·2026

Synthesis of Tropono-β2,3-Amino Acid Derivatives via Benzene-to-Tropone Skeletal Editing.

Organic letters·2026

New-Onset Convulsive Status Epilepticus Temporally Associated With Accidental Inhalation of Billygoat Weed (Ageratum conyzoides) Smoke: A Case Report.

Cureus·2026

Angelica sinensis polysaccharide inhibits pyroptosis and improves osteoarthritis through the collaborative power of PPARγ and Nrf2.

Frontiers in pharmacology·2026

Microbial volatile organic compounds in plant defense: mechanisms, signaling networks, and agricultural applications.

World journal of microbiology & biotechnology·2026

Antischistosomal Ozonide Glycine Ethyl Esters.

ACS medicinal chemistry letters·2026

Related Experiment Videos

Metabolic activation of N-hydroxy compounds by conjugation

Related Concept Videos

Changes in aldehyde dehydrogenase during rat urinary bladder carcinogenesis.

Oxidation of N-butyl-N-(3-formylpropyl)nitrosamine to N-butyl-N-(3-carboxypropyl)nitrosamine in rat liver and inhibition by disulfiram.

Inhibition of DNA methylase activity by acrolein.

Influence of disulfiram on the metabolism of the urinary bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine in the rat.

Induction of repair synthesis of DNA in primary cultures of rat urothelial cells by derivatives of the bladder carcinogen, N-n-butyl-N-(4-hydroxybutyl)nitrosamine.

Comparative carcinogenicity of N-butyl-N-(3-carboxypropyl)-nitrosamine and N-butyl-N-(4-hydroxybutyl)nitrosamine for the urinary bladder of (C57BL/6 X DBA/2)F1 mice.

Inhibiting CYP2A5 enzyme in mice decreases circulating cotinine after nicotine administration and increases dopamine in the brain.

Leucoseptoside a reverses multidrug resistance in breast cancer cells by targeting P-glycoprotein (P-gp/ABCB1) transporter.

Oxycodone Alleviates Post-anesthesia Cognitive Impairment in the Elderly via miR-150-5p/H731 axis.

In vitro and in vivo intestinal and hepatic oxidative metabolism of typical cytochrome P450 3A substrates, midazolam, nifedipine, and quinidine, in minipigs: a comparison with humans, monkeys, and dogs.

Formaldehyde directly induces cytotoxicity in human lymphocytes through ROS formation, mitochondrial/lysosomal destruction and oxidative stress; analysis of the protective effects of crocin.

An LC-MS/MS method for simultaneous quantification of six components of Angelicae pubescentis radix and systematic evaluation of Angelicae pubescentis radix as a potential inhibitor of multiple cytochrome P450 enzymes.

Total Synthesis of (±)-Caryopincaolide A.

Synthesis of Tropono-β2,3-Amino Acid Derivatives via Benzene-to-Tropone Skeletal Editing.

New-Onset Convulsive Status Epilepticus Temporally Associated With Accidental Inhalation of Billygoat Weed (Ageratum conyzoides) Smoke: A Case Report.

Angelica sinensis polysaccharide inhibits pyroptosis and improves osteoarthritis through the collaborative power of PPARγ and Nrf2.

Microbial volatile organic compounds in plant defense: mechanisms, signaling networks, and agricultural applications.

Antischistosomal Ozonide Glycine Ethyl Esters.

Related Experiment Videos

Metabolic activation of N-hydroxy compounds by conjugation

Related Concept Videos

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