Related Experiment Videos
The Dyggve-Melchior-Clausen syndrome
Birth Defects Original Article Series
|February 1, 1971
Abstract:
An 18-year-old mentally retarded girl with short-trunked dwarfism is described as a case of the Dyggve-Melchior-Clausen syndrome. This disorder is characterized by distinctive skeletal radiographic changes, particularly a lacey appearance of the iliac crest. This syndrome appears to be inherited as an autosomal recessive trait. Reports of several cases with similar radiographic changes but without mental retardation suggest heterogeneity within this syndrome.