Sextuplet pregnancy

Area of Science:

• Reproductive Endocrinology
• Maternal-Fetal Medicine
• Neonatology

Background:

• Gonadotrophin therapy can lead to multiple gestations, posing significant risks.
• Sextuplet pregnancies are exceptionally rare and present complex management challenges.

Purpose of the Study:

• To report on the management and outcomes of a rare sextuplet pregnancy.
• To highlight the complications associated with high-order multiple gestations following assisted reproductive technology.

Main Methods:

• Case report of a patient undergoing gonadotrophin therapy resulting in sextuplet pregnancy.
• Management included monitoring for pregnancy complications and delivery via cesarean section.

Main Results:

• The pregnancy experienced threatened abortion, premature labor, and placental insufficiency.
• Delivery at 32 weeks via cesarean section resulted in five thriving liveborn infants.
• One fetus was a macerated stillbirth.

Conclusions:

• High-order multiple pregnancies, such as sextuplets, require intensive maternal and neonatal care.
• While outcomes can be positive for some infants, risks of fetal demise and prematurity remain significant.