Acetylcholine receptors: number and distribution at neuromuscular junctions in rat diaphragm

The number of acetylcholine receptors per motor end plate in the rat diaphragm, measured by the binding of [(125)1]alpha-bungarotoxin, varies directly with rat size and is (4.0 +/- 0.2) x 10(7) for full-grown male rats. Autoradiographic analysis of single fibers labeled with this substance reveals that virtually all of these receptors are localized in the end plate.