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Sucrose malabsorption in Greenland.

A McNair, E Gudmand-Hoyer, S Jarnum

    British Medical Journal
    |April 1, 1972
    PubMed
    Summary
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    A study in Greenland found a high incidence of sucrose malabsorption (10.5%) in the population. This condition, present from birth, has significant clinical implications for infants, unlike lactose malabsorption.

    Area of Science:

    • Human physiology
    • Gastroenterology
    • Nutritional science

    Background:

    • Sucrose malabsorption is a condition affecting carbohydrate digestion.
    • Previous global incidence data for sucrose malabsorption is limited.
    • High rates of infant malnutrition and diarrhea are reported in Greenland.

    Purpose of the Study:

    • To estimate the incidence of sucrose malabsorption in a Greenlandic population.
    • To compare the prevalence of sucrose malabsorption with lactose malabsorption in the same population.
    • To highlight potential clinical implications of sucrose malabsorption in infancy.

    Main Methods:

    • Population-based study involving 190 individuals on the western coast of Greenland.
    • Sucrose tolerance tests were administered to assess sucrose absorption.

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  • Small-intestinal disaccharidase activity was measured in a subset of 19 patients.

    • Main Results:

    • Sucrose malabsorption was identified in 10.5% of the studied population.
    • This incidence is notably higher than previously reported globally.
    • The prevalence of sucrose malabsorption is lower than lactose malabsorption (54%) in Greenlandic Eskimos.

    Conclusions:

    • The high incidence of sucrose malabsorption in Greenland warrants further investigation.
    • Sucrose malabsorption, being congenital, may contribute to infant malnutrition and chronic diarrhea in the region.
    • Understanding sucrose malabsorption is crucial for pediatric health in Greenland.