Necropsy findings in a case of progressive vaccinia

A case of progressive vaccinia complicating chronic lymphocytic leukaemia is reported. At necropsy a vaccinial pneumonia, focal pancreatitis, and evidence of disseminated intravascular coagulation were found. Epithelial proliferation was noted in sweat glands, bronchi, and pancreatic ducts associated with lesions in these sites. The significance of these findings is discussed.