The molecular genetics of human cancer and its etiologic implications

MUC1 inhibition leads to decrease in PD-L1 levels via upregulation of miRNAs.

Leukemia·2017

MUC1-C integrates PD-L1 induction with repression of immune effectors in non-small-cell lung cancer.

Oncogene·2017

MUC1-C activates BMI1 in human cancer cells.

Oncogene·2016

DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells.

Oncogene·2016

MUC1-C activates the TAK1 inflammatory pathway in colon cancer.

Oncogene·2015

Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells.

Oncogene·2013

Nervous System Integrity in Drosophila: Essential and Dosage-Sensitive Roles of Hsp110.

Genetics·2026

Response to divergent selection on meiotic recombination in Saccharomyces cerevisiae.

Genetics·2026

Sex-specific control of locomotor behavior by neuronal Arhgef10 in aged Drosophila.

Genetics·2026

Context-dependent genetic regulation of gene expression in pigs.

Genetics·2026

Sperm-specific fertility factors SMZ-1/2 promote FB-MO biogenesis and MSP filament assembly in C. elegans.

Genetics·2026

Gene expression is stable despite widespread cis and trans regulatory divergence in Saccharomyces yeasts.

Genetics·2026

WDR12 Promotes Glucose Metabolism via PFKFB4 Upregulation in Gastric Cancer.

Cancer science·2026

Human Monocytic Models Reveal Genotype-Dependent Inflammatory Programs in VEXAS Syndrome.

Arthritis & rheumatology (Hoboken, N.J.)·2026

Phenotype-Specific Association of LHCGR rs13405728 Polymorphism with Anovulatory Infertility in Malay Women with Polycystic Ovary Syndrome: A Case-Control Study.

International journal of fertility & sterility·2026

Combined Effects of 7,12-dimethylbenz[a]anthracene (DMBA) with Cobalt, Cadmium, or Zinc on Fertility in Rats.

International journal of fertility & sterility·2026

Global, regional, and national burden of colorectal cancer attributable to modifiable risk factors, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.

Journal of gastrointestinal oncology·2026

Association between metabolic dysfunction-associated steatotic liver disease and risk of early-onset advanced colorectal neoplasia: a systematic review and meta-analysis.

Journal of gastrointestinal oncology·2026

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The molecular genetics of human cancer and its etiologic implications

Related Concept Videos

MUC1 inhibition leads to decrease in PD-L1 levels via upregulation of miRNAs.

MUC1-C integrates PD-L1 induction with repression of immune effectors in non-small-cell lung cancer.

MUC1-C activates BMI1 in human cancer cells.

DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells.

MUC1-C activates the TAK1 inflammatory pathway in colon cancer.

Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells.

Nervous System Integrity in Drosophila: Essential and Dosage-Sensitive Roles of Hsp110.

Response to divergent selection on meiotic recombination in Saccharomyces cerevisiae.

Sex-specific control of locomotor behavior by neuronal Arhgef10 in aged Drosophila.

Context-dependent genetic regulation of gene expression in pigs.

Sperm-specific fertility factors SMZ-1/2 promote FB-MO biogenesis and MSP filament assembly in C. elegans.

Gene expression is stable despite widespread cis and trans regulatory divergence in Saccharomyces yeasts.

WDR12 Promotes Glucose Metabolism via PFKFB4 Upregulation in Gastric Cancer.

Human Monocytic Models Reveal Genotype-Dependent Inflammatory Programs in VEXAS Syndrome.

Phenotype-Specific Association of LHCGR rs13405728 Polymorphism with Anovulatory Infertility in Malay Women with Polycystic Ovary Syndrome: A Case-Control Study.

Combined Effects of 7,12-dimethylbenz[a]anthracene (DMBA) with Cobalt, Cadmium, or Zinc on Fertility in Rats.

Global, regional, and national burden of colorectal cancer attributable to modifiable risk factors, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.

Association between metabolic dysfunction-associated steatotic liver disease and risk of early-onset advanced colorectal neoplasia: a systematic review and meta-analysis.

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The molecular genetics of human cancer and its etiologic implications

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